Botulinum Toxin Injection Therapy for Abductor Spasmodic Dysphonia Abductor spasmodic dysphonia (ABSD) occurs in 15% of persons affected with spasmodic dysphonia. This form of spasmodic dysphonia is less well understood than adductor spasmodic dysphonia (ADSD), and persons with this disorder do not receive as much benefit from botulinum toxin type A (BOTOX®) treatment as do those affected ... Article
Article  |   March 01, 2004
Botulinum Toxin Injection Therapy for Abductor Spasmodic Dysphonia
Author Affiliations & Notes
  • Christy L. Ludlow
    Laryngeal and Speech Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD
Article Information
Speech, Voice & Prosodic Disorders / Voice Disorders / Articles
Article   |   March 01, 2004
Botulinum Toxin Injection Therapy for Abductor Spasmodic Dysphonia
SIG 3 Perspectives on Voice and Voice Disorders, March 2004, Vol. 14, 10-12. doi:10.1044/vvd14.1.10
SIG 3 Perspectives on Voice and Voice Disorders, March 2004, Vol. 14, 10-12. doi:10.1044/vvd14.1.10
Abductor spasmodic dysphonia (ABSD) occurs in 15% of persons affected with spasmodic dysphonia. This form of spasmodic dysphonia is less well understood than adductor spasmodic dysphonia (ADSD), and persons with this disorder do not receive as much benefit from botulinum toxin type A (BOTOX®) treatment as do those affected with ADSD (Blitzer, Brin, & Stewart, 1998). This is the topic that I was asked to address in this report. To do so, I will spend some time discussing what is known about the symptoms, the treatment responses of persons with ABSD to BOTOX®, and what is known about the pathophysiology underlying the symptoms of this form of spasmodic dysphonia. In conclusion, better understanding of the pathophysiology is needed in order to design better treatments for the disorder.
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